The immune-system balance of T helper 1 (TH1) cells and T helper 2
(TH2) cells is often at the root of many conditions, including
autoimmune issues, allergies, and increased susceptibility to infection.
Exercise is a known modulator of TH1 and TH2 balance, which may provide
a key advantage in restoring immune function. In this month’s
column, we explore how exercise may contribute to this balance and where
it may be most applicable.
The TH1/TH2 response is recognized as a contributor to imbalances
in immune function. The TH1 cells are involved with cell-mediated or
innate immunity, thus helping the body deal with intracellular pathogens
like viruses, yeast, and intracellular bacteria (mycoplasma mycoplasma
Any of the bacteria that make up the genus Mycoplasma. They are among the smallest of bacterial organisms. The cell varies from a spherical or pear shape to that of a slender branched filament. , chlamydia,
and so on). On the other end of the spectrum is the TH2 subset, which is
involved in humoral hu·mor·al
1. Relating to body fluids, especially serum.
2. Relating to or arising from any of the bodily humors.
Pertaining to or derived from a body fluid.